Introduction
Calcium Pantothenate, widely recognized as Vitamin B5, stands as a critical nutrient in the B-complex family. Marketed under trade names like Calpan and Pantomin, this water-soluble vitamin serves as a cornerstone in dietary supplements, fortified foods, and pharmaceutical formulations. In this article, we delve into the science-backed benefits, mechanisms, and practical applications of Calcium Pantothenate, offering insights for manufacturers, brands, and health-conscious consumers.

What Is Calcium Pantothenate?
Calcium Pantothenate is the calcium salt of pantothenic acid, commonly referred to as Vitamin B5. As an essential nutrient, it must be obtained through diet or supplementation. Its stability and bioavailability make it the preferred form for industrial and commercial use in:

  • Dietary supplements (tablets, capsules, powders)

  • Functional food and beverage fortification

  • Animal feed premixes

  • Pharmaceutical preparations

Key Health Benefits and Applications

  1. Energy Metabolism Support
    Calcium Pantothenate is a precursor to coenzyme-A (CoA), a vital molecule in the Krebs cycle and fatty acid metabolism. This role makes it indispensable for converting macronutrients into cellular energy (ATP).

  2. Stress Response and Hormonal Balance
    Often termed the “anti-stress vitamin,” it supports adrenal gland function and aids in synthesizing stress hormones like cortisol. It also contributes to the production of neurotransmitters, promoting nervous system health.

  3. Skin and Wound Healing
    Research highlights its role in promoting skin barrier repair and collagen synthesis. It is increasingly used in topical formulations and supplements targeting dermatological health.

  4. Cholesterol and Lipid Synthesis
    As a cofactor in cholesterol production, it helps maintain cell membrane integrity and supports steroid hormone synthesis.

Mechanism of Action
Upon ingestion, Calcium Pantothenate hydrolyzes into pantothenic acid, which the body converts into:

  • Coenzyme-A (CoA): Central to energy production and macronutrient metabolism.

  • Acyl carrier protein (ACP): Essential for fatty acid biosynthesis.

These coenzymes drive mitochondrial function, neurotransmitter synthesis (e.g., acetylcholine), and hormonal regulation, underscoring their systemic importance.

Dosage and Forms

  • Typical Adult Dosage: 5–10 mg/day for maintenance; higher doses (up to 500 mg) may be used therapeutically under medical supervision.

  • Available Forms: Powder (ideal for OEM/ODM manufacturing), tablets, and capsules.

  • Onset of Effects: Benefits accumulate over weeks to months, though deficiency states may show improvement within days.

Safety and Considerations

  • Side Effects: Rare and mild (e.g., gastrointestinal discomfort). Excess amounts are excreted renally due to water solubility.

  • Contraindications: Hypersensitivity to pantothenic acid. Caution advised during pregnancy or lactation.

  • Drug Interactions: May interact with oral contraceptives and tetracycline antibiotics; consult healthcare providers when combining with other B-vitamins.

Industrial and Commercial Applications
For manufacturers seeking GMP-grade, non-GMO, and food-grade ingredients, Calcium Pantothenate offers:

  • Stability in formulations

  • Flexibility in dosing and delivery systems

  • Compliance with global standards (BP, USP, EP)

Why Source from Xi’an Herb Bio-Tech?
As a trusted supplier and manufacturer of high-purity nutraceuticals, we provide:

  • Bulk Calcium Pantothenate powder with customizable particle size

  • Full documentation (COA, TDS, MSDS)

  • Competitive MOQs and private labeling options

  • Shelf-stable products with guaranteed 24-month shelf life

Conclusion
Calcium Pantothenate remains a versatile, evidence-backed ingredient for energy, stress management, and metabolic health. Whether you’re developing supplements, functional foods, or animal nutrition products, its broad applicability and safety profile make it an invaluable component.

Interested in samples, pricing, or technical data? Contact us to discuss your specific requirements and request a quotation tailored to your needs.