Table of contents

  • Product introduction
  • Benefits of nattokinase
  • Basic dosage of nattokinase
  • Nattokinase precautions and contraindications
  • Can nattokinase dissolve plaque in blood vessels?
  • Is nattokinase good for the liver?
  • Can nattokinase be taken for a long time?

 

 

Nattokinase (NK for short) is a subtilisin protein kinase, a serine protease produced by Bacillus subtilisl natto during natto fermentation. It can dissolve thrombus, reduce blood viscosity, improve blood circulation, soften and increase blood vessel elasticity, inhibit platelet coagulation, and help prevent hypertension and arteriosclerosis.

 

  • Product introduction

Nattokinase (NK) is extracted from food natto or produced by natto bacteria. It is a protein with a molecular weight much smaller than UK, SK, and tPA, and can be absorbed by the intestine. The in vitro and in vivo thrombolysis of nattokinase The properties have also been confirmed through experiments. At the same time, it is concluded that the thrombolytic activity of nattokinase in vivo is four times that of plasmin. It acts rapidly and lasts for a long time in the body. fibrinolytic activity. Patients at risk of myocardial infarction need to invest 300,000 units of urokinase at a time, and 50 grams of natto contains 800,000 units of urokinase for thrombolysis.

According to the Nikkei Sangyo Shimbun, the researchers gave subjects a cultured extract of nattokinase and then tested their blood. They found that after consuming the extract for 6 hours, the clotting of the subjects’ platelets was inhibited. The researchers concluded that nattokinase has the function of dissolving thrombus and smoothing blood flow.

Therefore, nattokinase has become a new type of oral thrombolytic drug (second-generation thrombolytic drug), which plays an active role in the prevention and treatment of cardiovascular and cerebrovascular embolism and embolic Alzheimer’s disease.

  • Benefits of nattokinase

Nattokinase has a thrombolytic effect. Nattokinase has a short duration of action, a long duration of efficacy and high safety.

Nattokinase originated from Japan’s traditional fermented food natto, a protease produced from Bacillus subtilis natto, which has the effect of dissolving blood clots and reducing blood cholesterol. However, because it is not used clinically and is only used in the market as a health care product, do not eat it by yourself, and pay attention to some taboos in the eating process. It is not recommended for people with severe diarrhea, vomiting, indigestion and bleeding tendency to avoid increasing the risk of bleeding.

  1. The most significant effect of nattokinase is thrombolysis, which can dissolve thrombus in human blood, which is also the main reason for the pharmacological effect of nattokinase.
  2. Nattokinase can inhibit the growth of bacteria that are harmful to the human body. The mechanism is that nattokinase can produce dipicolinic acid bactericidal substances in the human body, thereby exerting the antibacterial effect of nattokinase.
  3. Nattokinase is not affected by the strong acid of gastric juice, and directly acts on the human intestine, promoting gastrointestinal regulation, moisturizing and defecation, and achieving the effect of detoxification and beauty.
  4. Nattokinase can effectively reduce blood viscosity, change platelet coagulation state, reduce cardiovascular and cerebrovascular pressure, effectively protect cardiovascular and cerebrovascular, and prevent various cardiovascular and cerebrovascular diseases such as atherosclerosis and cerebral hemorrhage.
  5. Nattokinase can lower blood lipids and blood pressure while eliminating excess cholesterol. For people with three highs, nattokinase is a good regulator to relieve symptoms of three highs.
  6. In addition, nattokinase can promote liver cell regeneration, improve liver function, and enhance liver detoxification ability, thereby preventing and improving fatty liver, and playing the role of hangover and liver protection.
  • Basic dosage of nattokinase

The Japan Nutrition and Health Food Association stipulates that the daily normal maintenance amount of nattokinase should not be less than 2000FU. Therefore, medical nutrition experts recommend that the basic dosage of nattokinase is as follows:

  1. The daily intake is 2000FU, which is the dosage for normal or sub-healthy people to prevent cardiovascular and cerebrovascular diseases. Most people have a reaction after taking it for about 7 days, and they feel energetic and dry eyes. The symptoms began to improve; sensitive people responded on the same day.
  2. The daily intake of 2000FU-4000FU is the recommended dosage for patients with cardiovascular and cerebrovascular diseases. Most of the body has a positive reaction in about 15 days, such as cold hands and feet, chest tightness, palpitation, numbness, dizziness, insomnia and other symptoms gradually relieved, 2-3 The blood pressure and blood lipid indicators gradually approach the normal values ​​in about a month, and when the indicators are normal, the dose can be reduced to the healthy maintenance amount.
  3. The daily intake of 4000FU-6000FU is the recommended dosage for patients with severe cardiovascular and cerebrovascular diseases. The symptoms begin to slow down around January, and the slowdown is obvious after 3 months. After the indicators improve, the dosage can be gradually reduced.
  • Nattokinase precautions and contraindications
  1. Not recommended for pregnant women.
  2. Suspend food for 2 weeks before and after surgery to avoid affecting wound healing.
  3. Severe diarrhea, vomiting, indigestion.
  4. For other diseases related to blood coagulation, please consult a doctor before eating. If there is a lot of bleeding, such as ruptured blood vessels, accidents, etc., it should also be avoided. Such as cerebral hemorrhage patients should be suitable for consumption 3 months after the onset of symptoms.
  5. Those who use large doses of thrombolytic drugs during treatment.
  6. The people after stenting should follow the doctor’s advice.

Note: Nattokinase is a functional food and cannot replace a drug.

 

  • Can nattokinase dissolve plaque in blood vessels?

 

Nattokinase can dissolve plaque in blood vessels.

Natto hormone has the functions of dissolving thrombus, reducing blood viscosity, improving blood circulation, softening and increasing blood vessel elasticity, and can be used to treat carotid plaque formation. Anticoagulant and thrombolytic drugs for plaque formation have a risk of plaque shedding, but the probability is very low, and this risk is mainly related to the nature of the plaque itself. There is a powerful thrombolytic in natto named nattokinase. This is a thrombolytic drug. It is actually produced after soybean fermentation. It has exaggerated ingredients. It is best to go to a regular hospital for examination and treatment. Blood sugar, proper exercise, low-salt and low-fat diet, avoid fatigue, eat more vegetables and fruits, and actively supplement vitamin C.

Nattokinase can dissolve blood clots in some studies, but under certain conditions, that is, nattokinase can dissolve blood clots in in vitro experiments, but if taken, it usually does not dissolve blood clots. Nattokinase is a protein, Just like the usual eggs. After entering the digestive tract, it will be decomposed and digested by the digestive tract, and cannot enter the human body, blood vessels and tissues in the form of nattokinase. However, under specific conditions such as laboratories, petri dishes and test tubes, it can effectively dissolve blood clots . Because nattokinase is not a drug, it is still a health product in China. If it is injected directly into the blood vessels, it may cause more severe allergic reactions and be more dangerous. You should be cautious about nattokinase. The main reasons are increased blood viscosity, decreased blood flow velocity and vascular endothelial cell damage. In daily life, try to avoid eating high-fat foods, including fatty meat, animal offal, caviar, etc., so as not to cause hyperlipidemia and aggravate the disease. You should also quit smoking and drinking. Smoking and drinking may damage vascular endothelial cells. Cause vasospasm and aggravate the disease.

  • Is nattokinase good for the liver?

Nattokinase is good for the liver and can play a protective role. Nattokinase, also known as subtilisin protease, is a serine protease produced by Bacillus subtilis natto in the process of natto fermentation. It has the functions of dissolving thrombus, reducing blood viscosity, improving blood circulation, softening and increasing blood vessel elasticity.

After nattokinase is absorbed by the human body, it enters the human liver system to help share the anti-alcohol pressure on the liver, so that alcohol can be better decomposed and eliminated. At the same time, nattokinase will penetrate into the digestive system, accelerate the secretion of acidic substances in the digestive system, accelerate the decomposition rate, and reduce the damage caused by alcohol to the liver, which plays a protective role. Nattokinase can also regulate and improve blood pressure from the side by regulating individual blood pressure and thickening the walls of blood vessels in the human body, thereby reducing vascular resistance. For hypertensive patients, taking nattokinase products in combination with antihypertensive drugs can gradually restore normal blood pressure and reduce the frequency of hypertension symptoms such as dizziness and headache. Nattokinase also has excellent antioxidant capacity, which is about 20 times that of ordinary vitamins. Therefore, for women, taking this product can protect blood vessels from attack, delay aging, and prevent Alzheimer’s disease.

Nattokinase is not suitable for people with hemophilia, because hemophilia is a bleeding disorder caused by a lack of clotting factors, and nattokinase has anticoagulant properties. Consuming nattokinase in people with hemophilia blocks blood clotting and is dangerous. Nattokinase has strong anticoagulant ability. If it is given to patients who have just undergone surgery or whose wounds have not yet healed, it is easy to cause the wounds to fail to coagulate and heal. Therefore, it is not recommended to take nattokinase while the wound is not healing. Pregnant women taking nattokinase easily interfere with normal coagulation supplementation.

  • Can nattokinase be taken for a long time?

Nattokinase is best not to eat for a long time.

Because nattokinase is long-term, it may cause bleeding and oozing of skin and internal organs, or if patients take nattokinase for a long time after stent surgery, it may also cause lesions in the body. Although nattokinase has a very good effect, such as it can inhibit the aggregation of platelets and help to resist thrombosis. However, it must be used under the guidance of a doctor during the treatment process. Do not use nattokinase for treatment without authorization. If it is used improperly, it may cause some side effects. Clinically, if it is a thrombotic disease, it is best to go to the hospital for a regular system examination, and then follow the doctor’s guidance and use regular drugs for treatment.

 

The above content is some knowledge about nattokinase that we bring to you today for your reference.

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