What is Saffron extract?
Saffron extract is extracted by the raw material extraction of the SACUS Sativus L. It also contains a small amount of alien melin, mountains, and vitamin B1 and vitamin B2. The saffron extract solution is a powerful removal agent of hydroxy radical and supersonic free radicals. It can antioxidant reactions, improve mitochondrial function, inhibit the apoptosis of the optic nerve cells, and also improve microcirculation, improve immunity, antiplication arteriosclerosis, antioxidant, and antioxidant. Blood lipids, bile prevent liver, prevent osteoporosis, and protect the kidneys.
Plant source
[Base source] The upper and stigma of the railus SACUS Sativus L. flowers.
[Alias] Fan Red Flowers, Western Red Flowers.
[Distribution] Beijing, Shanghai, Shandong, Zhejiang, Sichuan, Xinjiang, etc. There are a small amount of experimental cultivation. Spain, Iran, Italy, Germany, France, Greece, Austria, the former Soviet Union and Japan all have cultivation.
[Plant form] Perennial herb. The underground bulbs are spherical, and the outer brown membrane is like a leaf. Born from the bulb, non -reciprocating, narrow and long -line leaves, rolls of leaf margins, with fine hairs. Flowers, round ovate, pale purple, thin tubular tubing. The fruits, long -shaped, have three blunt edges, and start to reach the ground when the fruit matures. Most of the seeds, spherical, seed leather.
The chemical composition of saffron
1.Volatile oil
The volatile oil components in the stagnation (stigma) of the Tibetan red flower crown (stigma) are degraded by carotene and other carotenoids such as corn yellow quality. The structure is special. Among them, the tibetan aldo is mainly tibetan in the triple -based ethylene derivatives, which accounts for 72 %of the total amount of oil. It It is the degradation product of the bitterness of saffron, and it is also the quality control indicator of the Chinese medicine Zang Honghua -. Some scholars identified 46 compounds from the volatile oil of saffron, accounting for 90.99%of the total amount of oil. Among them, 5 keto compounds account for 6.16%, 5 aldehyde compounds account for 2.39%, 6 alcoholic compounds account for 4.98%, 6 acid compounds account for 19.77%, 8 olefin compounds account for 36.42%, olefin oxide oxides Two of them account for 5.74%, 8 alkaid compounds account for 12.5%, 2 ester compounds account for 0.48%, and 4 other compounds account for 2.55%. In the identified Tibetan saffron wave oil components, the relatively high content is mainly olefin and olefin oxides, which belongs to the cricket compounds. In addition, the relatively high content is acidic compounds.
2.Flavonoids
Flavonoids are mainly distributed among the flowers of saffron. The common ones are purple clouds, chimotin 3-pendant beanhoglycoside, Shannin-3-glucanhoglycoside and Shannu-3-3- Glucose glucoside, flying swallow grass, triteromey femorrin grass, and so on.
3.Volatile oil
The drying and storage of saffron stigma through different degradation paths produced through different degradation paths, which belong to the achinide compounds of the triterical ring, and mainly include saffron bitter elements. Salva is the main bitter ingredients of saffron. It can be converted into saffron aldehyde under acid or alkaline conditions or under the action of enzymes.
4.Polyxiene and its glycoside
Polymorne and its schine are the main colored ingredients in the saffron of Chinese medicine. It mainly includes the following two categories:
(1) Carotene and its glyc
Tibetan erythronic acid is the main component of carotene and its glycoside. Including carotenoids, safflower acid and its glycoside, such as dragon bilonal glycoside, glycoside, -dragon glycoside, glycoside, and hyperlide; B-Tibetan safflowic acid, C-Tibetan saffron acid and so on.
(2) Carotene category
There are mainly A, B-carotene, such as lycopene and corn yellow.
5.Others
It mainly includes phenols, chimotonase, triangular saponin, and soderoside.
The benefits of saffron extract
1.The role of the uterus
Saffron extracts have excited effects on mice, guinea pigs, rabbits, dogs, and cats in the body uterus. The pregnancy of the pregnant uterus is more sensitive; the intensity order of the various extracting solution of the red tubing is: decoction> Ethanol extract> Volatal ingredients> Effective extract. The role of excitement uterus can be blocked by partial parts of ethyladic acid wheat poxine, which is not sensitive to atropine. Essence
2.Effect on the circulatory system
Salva extracts can reduce the anesthesia dogs and cat blood pressure, and can maintain it for a long time, which has an excitement of breathing. The kidney volume shrinkage during antihypertensive, showing kidney blood vessel contraction, and also contracted to toad blood vessels. It has a significant inhibitory effect on the heart of a bodies. After chemical analysis, the composition of the heart is related to potassium salts. Therefore, the pharmacological research of safflower should first remove potassium salts.
3.The role of anti -tumor
The saffron preparation has obvious cancer suppression and anti -cancer capabilities, especially the saffron extract (ethyl -based safflower acid) to leukemia, ovarian cancer, colon cancer, transverse muscle sarcoma, colon cancer, nipple sarcoma, flat cytoma, and soft tissue sarcoma. Strong inhibitory effect. Its anti-cancer mechanism may be to destroy the DNA synthetic enzyme system, that is, the DNA-protein connection medium that is vital to the cell DNA synthesis such as the topology of the topology such as topology II, thereby inhibiting the synthesis of DNA and RNA, and achieving the role of inhibiting tumor cell growth. Essence In addition, saffron substances also inhibit the activity of cell protein kinase and the expression of primary cancer genes.
4.The role of liver and gallbladder
Salva extract has a sharp bile effect, and the effective ingredients are sodium saffral sodium salt and saffron acid ester. α-tibetic acid can reduce cholesterol and increase fat metabolism. It can cooperate with traditional Chinese medicine such as hawthorn, grass decision, and diarrhea for the treatment of fatty liver.
5.Antioxidant effect
Salva extracts, especially saffron, can effectively inhibit the activity of oxygen free radicals and mucine oxidase, showing antioxidant biological activity.
6.Protect the kidneys
By studying the Rat C-BSA nephritis model, it was found that the proteinuria phenomenon of rats was reduced and the degree of renal damage was reduced. Among them, the saffron is mainly through inhibiting epoxy enzymes and reducing the synthesis of prostaglandin. It has achieved the function of kidney capillaries smoothly, increased blood flow, and promoting the repair of inflammatory damage. Tips, Tibetan saffron can interfere with the occurrence of kidney inflammation by improving the release of platelets and inflammatory medium.
7.Intervention of arrhythmia
The effective ingredients of saffron extracts have a good role in confronting the role of ventricular arrhythmia models induced by oxoline, Kabain, and calcium chloride, which provides an experimental basis for Tibetan saffron for the treatment of arrhythmia, and for further development It provides a feasibility basis for studying saffron as an anti -cardiac and myocardial ischemia. It is prompted that the saffron may be called a new type of Chinese medicine to prevent cardiovascular and cerebrovascular diseases.
8.Regulate immune function
Salva extract has obvious effects of promoting blood circulation and removing blood stasis, antibacterial and anti -inflammatory effects, and then enhance the body’s endurance, increase the content of immune cells, in order to improve the human body’s immunity, play a role in adjusting the body’s qi and blood, and balance the human yin and yang.
9.Prevention and treatment atherosclerosis
Safflower extract has good curative effects in terms of blood lipid regulating blood lipids and lowering blood pressure.
10.Retina protection effect
The New Zealand-free-free animal model is made, and the tibetan safflower extract of the dose is injected from the vein of the ear edge, once a day, and set up a high-pressure control group. Results showed that the number of retinal ganglia cells in the treatment group was significantly more than the high -pressure control group (P <0.05), indicating that the saffron extract solution was used to improve the blood circulation of the retina and block the ischemia and hypoxia of the retinal ganglia (the ischemia low oxygen -to -oxygen ganglion cell ( RGC) damage has a protective effect on RGC. It is prompted that the saffron extract may be protected by the RGC -based damage to the RGC membrane structure, sub -cellular and nucleus by reducing the free radicals in the retina to prevent the free radicals.
11.Other functions
Salt Ethanol extract (CSE) can prevent the inhibition of the long -term enhancement effect (LPT) of the hippocampus of ethanol bow |. In the anesthesia mice, CSE (250 mg: kg -1) can also effectively prevent the LPT suppression of the acetaldehyde bow | without affecting the learning function of mice. The water extraction solution of saffron can significantly inhibit the reproductive toxicity produced by anti -cancer drugs such as cisplatin, cycclophosphamide, fillemidin C (Mitomy Cin C), and amino -based ethyl (mitomy cin c), and the toxicity of anticancer drugs, and The size of the inhibitory effect is not significant and dose. This is mainly because the saffron extract significantly reduces the impact of reproductive toxicity on hepatium glutadans sigyase (GST).
Side effects of saffron extract powder
- Stimulate the uterus. Tibetan saffron has the effect of promoting blood circulation. Women of menstrual periods are mainly manually manually increased, abdominal pain, and women during pregnancy can have a miscarriage because of the shrinkage of the uterus.
- Stimulate nerves. If the use of saffron for a long time can cause convulsions, even sluggish and trembling.
- Endocrine disorders. Improper use of saffron can cause endocrine disorders, and a few patients may develop dizziness and rash.
- Improper use of saffron may also cause fire. After getting angry, you must stop the saffron in time.
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