Salvia miltiorrhiza extract is from the dried root and rhizome of Salvia miltiorrhiza Bunge.

In the research of Salvia miltiorrhiza, some are  fat-soluble components, some are water-soluble components, and some retain both fat-soluble and water-soluble components, but in particular, no matter what the extracted components are, it has the effect of promoting blood circulation and removing blood stasis. Therefore, the main components and pharmacological effects of Danshen are really worthy of in-depth study.

At present, more than 20 water-soluble components and more than 50 fat-soluble components have been isolated from Salvia miltiorrhiza. The water-soluble components are mainly phenolic acid compounds, such as 3,4-dihydroxyphenyl lactic acid and salvianolic acid B , Protocatechuic aldehyde, Caffeic acid, Rosmarinic acid, etc.; fat-soluble components are mainly conjugated and ketone compounds, such as tanshinone , Tanshinone ⅡA, Cryptotanshinone, etc. Modern pharmacological studies have shown that most of the water-soluble components of Salvia Miltiorrhiza have anti-oxidation, anti-coagulation, and anti-myocardial ischemia effects, which are closely related to traditional functions such as “activating blood and removing blood stasis”; while the fat-soluble components mainly composed of tanshinones have antibacterial properties. , Anti-inflammatory, nervous system protection and anti-myocardial ischemia, myocardial protection and endothelial cell protection.

Tanshinone products are fat-soluble phenanthrenequinone compounds with antibacterial effect extracted from the traditional Chinese medicine Salvia miltiorrhiza Bunge. More than 10 tanshinone monomers such as tanshinone I, tanshinone ⅡA, tanshinone ⅡB, cryptotanshinone, isocryptotanshinone, etc. were obtained. Among them, cryptotanshinone, dihydrotanshinone Ⅱ, hydroxy tanshinone, tanshinone methyl ester, and tanshinone Ⅱ B have antibacterial effects, as well as anti-inflammatory and cooling effects. The sulfonated product of Tanshinone ⅡA, Tanshinone ⅡA Sodium Sulfonate, is soluble in water. Clinical trials have proved that it has a significant effect on the treatment of angina pectoris and has low side effects. The total tanshinone has many functions such as antibacterial, anti-inflammatory, promoting blood circulation and removing blood stasis, and promoting wound healing. There are no obvious side effects after long-term use.

Tanshinones:

Tanshinone ⅡA, cryptotanshinone, tanshinone Ⅰ, dihydrotanshinone, total tanshinone, tanshinone ⅡA sodium sulfonate, etc.

Application of Tanshinone ⅡA

1.Medicines

2.Health Products

3.Daily chemical products

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