Citrus Aurantium Extract

• Supply Ability : 500-1000 Kilograms Per Month
• Minimum Order Quantity :Only 1 Kilograms
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Product Description

Citrus Aurantium Extract is derived from the dried immature fruit or peel of Citrus aurantium L. (bitter orange, also known as Seville orange or sour orange), a plant belonging to the Rutaceae family. The extract is standardized primarily to synephrine (p-synephrine), a protoalkaloid with adrenergic properties that has become the most extensively studied phytochemical in bitter orange .

The extract also naturally contains flavonoids (such as naringin, hesperidin, and neohesperidin), coumarins, and other phenylethylamines including octopamine and tyramine . Historically, bitter orange has been used in traditional medicine for digestive support, and its extract is now widely utilized in dietary supplements targeting metabolic support and thermogenesis .

Benefits & Application

1.Metabolic & Thermogenic Support

Synephrine, the primary active compound in Citrus Aurantium Extract, is a β3-adrenergic receptor agonist with documented thermogenic and lipolytic actions . Human trials have shown that C. aurantium and p-synephrine may increase resting metabolic rate and energy expenditure, as well as support weight management when administered over 6–12 weeks . The flavonoids present in the extract also contribute to these observed effects . For formulators developing metabolic support or weight management products, Citrus Aurantium Extract offers a well-researched botanical alternative.

2.Digestive Health Support

Citrus aurantium has a traditional history of use for improving indigestion, diarrhea, dysentery, and constipation . Modern research supports these traditional applications, with studies demonstrating that the extract’s alkaloid and flavonoid constituents contribute to gastrointestinal comfort and regularity.

3.Intestinal Anti-Inflammatory Potential

Preclinical research has demonstrated that a hydroalcoholic extract of C. aurantium significantly alleviated colonic mucosal inflammatory lesions in ulcerative colitis models. The extract markedly reduced the expression levels of pro-inflammatory mediators including interleukin-6, interferon-gamma, tumor necrosis factor-alpha, and monocyte chemotactic protein-1 in colonic inflammation . These findings suggest potential applications in gut-health formulations, though further clinical validation is needed.

4. Antioxidant Activity

The flavonoids abundant in Citrus Aurantium Extract—including hesperidin, naringin, and neohesperidin—function as direct antioxidants and free radical scavengers . These polyphenolic compounds contribute to the extract’s overall antioxidant profile, supporting cellular protection against oxidative stress.

5. Appetite & Energy Support

Synephrine’s structural similarity to ephedrine has led to its use as a substitute in formulations targeting appetite reduction and energy expenditure . While less potent than ephedrine in terms of cardiovascular effects, p-synephrine has been studied for its ability to support perceived energy and exercise performance, particularly when combined with caffeine .

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