Project Description

Rhynchophylline

  • Supply Ability : 500-1000 Kilograms Per Month
  • Minimum Order Quantity :Only 1 Kilograms
  • Packing:Aluminum foil bags,Fiber drums
  • Logistics: By Express(5-7 Days), By Air, By Sea
  • Payment : Western Union , T/T
  • Secure transaction

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Product Description

Rhynchophylline is a high-purity oxindole alkaloid monomer extracted and purified from the stems and hooked branches of Uncaria rhynchophylla (Rubiaceae). It is produced through low-temperature extraction, macroporous resin separation, and high-precision purification, yielding a colorless needle-shaped crystal powder with ultra-high purity and stable chemical properties.

Unlike crude Uncaria extracts, this monomer product removes impurities, residual pigments, and inactive components, retaining pure Rhynchophylline with consistent purity. It is specifically designed for pharmaceutical research and API applications, including pre-clinical pharmacological studies, new drug development, and neurological and cardiovascular research. It also serves as a standard monomer reagent for laboratory analysis and academic research.

Product Specifications

Parameter 
Specification Test Method
Purity  ≥ 98.0% HPLC
Appearance Colorless needle-like crystal powder Visual Inspection
Source Stems and hooked branches of Uncaria rhynchophylla Certificate of Origin
Loss on Drying  ≤ 2.0% USP <731>
Residue on Ignition ≤ 0.5% USP <281>
Heavy Metals (Total) ≤ 20 ppm ICP-MS
Lead (Pb)  ≤ 3.0 mg/kg ICP-MS
Arsenic (As) ≤ 1.0 mg/kg  ICP-MS 

Product Advantages & Scientific Basis

  • 98% High Purity Monomer: Strict purification process removes miscellaneous alkaloids and impurities, far higher than ordinary crude extracts, with more concentrated activity, accurate dosage and better developability, meeting pharmaceutical research and high-end functional formula standards.
  • Exclusive Authentic Plant Source: Selected high-quality Rubiaceae Uncaria rhynchophylla hooked branches as raw materials, with stable active ingredient content, avoiding raw material source confusion and ensuring consistent product efficacy.
  • Authoritative Scientific Research Support: Verified by multiple journals such as Frontiers in Pharmacology and British Journal of Pharmacology. It has clear pharmacological mechanisms in neuroprotection, vascular protection and anti-inflammation, with sufficient pre-clinical experimental data and clinical research basis.
  • Stable Biological Activity: Low-temperature whole-process processing protects the active structure of Rhynchophylline, avoids activity loss, and maintains long-term stable physical and chemical properties for formula development and experimental research.
  • Multi-Mechanism Synergistic Action: Acts as a non-competitive NMDA receptor antagonist and SIRT3 agonist, with dual regulatory effects on nervous system and cardiovascular system, featuring multi-target and high-efficiency characteristics.

Core Pharmacological Functions & Efficacy

1.Vascular Protection & Blood Pressure Regulation

Rhynchophylline effectively inhibits peripheral vasoconstriction, reduces vascular resistance, and improves vascular endothelial mitochondrial damage. It stably assists in lowering blood pressure, and has significant regulatory effects on renal hypertension and spontaneous hypertension. It also protects vascular endothelium and improves overall vascular health.

2.Anti-Thrombotic & Blood Lipid Modulation

It significantly inhibits platelet aggregation, reduces platelet adhesion rate, blocks thrombosis formation, and improves blood microcirculation. Meanwhile, it assists in regulating blood lipid levels, reducing blood viscosity, and preventing cardiovascular and cerebrovascular circulation disorders.

3.Neuroprotection & Central Calming Regulation

As a core neuroprotective ingredient, it reduces the loss of dopaminergic neurons, inhibits the secretion of inflammatory cytokines in nerve tissues, and relieves central nervous system excitement. It delivers mild sedative and calming effects, improves dizziness and neurasthenia, and supports the maintenance of normal neurological function.

4.Anti-Arrhythmia & Myocardial Protection

It can antagonize various drug-induced arrhythmias, stabilize myocardial electrical activity, reduce myocardial oxidative damage, and protect normal cardiac systolic and diastolic functions, effectively improving abnormal heart rhythm problems.

5.Traditional Herbal Therapeutic Properties

Inheriting the classic efficacy of Uncaria, it clears heat and calms the liver, relieves wind and relieves spasm. It effectively improves headaches, dizziness, bloating and discomfort caused by liver fire hyperactivity and liver wind internal movement, and relieves convulsions, muscle spasms and physical restlessness.

Commercial Application Scenarios

1.Functional Health Food & Dietary Supplements

Used in the development of cardiovascular care formulas, nerve-soothing health products, blood pressure and lipid regulation dietary supplements. With high purity and safe plant-based attributes, it meets international food-grade additive standards and is suitable for long-term daily wellness formula development.

2.Pharmaceutical Development & Biomedical Research

Widely used in pre-clinical pharmacological experiments, new drug development, and neurological & cardiovascular disease research. It is a key standard monomer reagent for studying NMDA receptor regulation, SIRT3 pathway mechanism and neurovascular protection.

3.Laboratory Reagents & Academic Research

98% high-purity standard product, specially applicable for laboratory content detection, botanical identification, pharmacological mechanism research and academic paper experimental analysis, providing accurate and repeatable experimental data support.

4.Custom Functional Raw Material Formulation

Support customized compound formula development, suitable for high-end plant-derived functional raw material formulation, covering multiple fields of human sub-health conditioning and organ protection.

Packing & Shipping

Packing & Shipping——Xi'an Herb Bio

Storage Instructions

Store the sealed powder in a cool, dry and ventilated environment, away from direct sunlight, high temperature, humidity and peculiar odors. After opening the package, seal tightly at all times to prevent moisture absorption and active ingredient loss. Refrigeration is recommended for long-term storage in humid and high-temperature regions to maintain stable powder activity and extend shelf life.

Quality Assurance & Export Standards

All batches of Rhynchophylline are strictly tested by HPLC, with purity up to 98% and stable batch quality. The product is natural, non-toxic, residue-free, and compliant with international export standards. Complete COA, test reports and technical specification documents are provided to support customer product registration, formula development and market sales.

Located in China, if you purchase from us,we offer many additional convenient services, all of which cannot be easilly provided by other ingeredient products suppliers. Welcome to contact us to get FREE SAMPLE, COA and Nutrition Facts!

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